Oral Side Effects Pose Growing Concerns

Australian dentists are cautioning users of GLP-1 weight-loss drugs about potential oral health issues, including dry mouth and an increased risk of cavities. This warning comes as Bupa research indicates that 1 in 5 Australians would consider these medications for weight loss.
The data reveals 57% of Australians wish to lose weight, with a significant 75% of women aged 40-49 expressing this desire. GLP-1 medications are effective in managing weight and chronic conditions, but their active ingredients can affect saliva flow, leading to unwanted effects.
Bupa Dental Principal Dentist Dr Mark Dohlad stated, “One of the potential concerns is dry mouth, which can occur with medications such as semaglutide, often indirectly through reduced fluid intake or dehydration.”

Impact of GLP-1 Medications

Originally developed for type 2 diabetes, GLP-1 medications have gained popularity for weight loss, with about half a million Australians using them monthly. This accounts for nearly 2% of the adult population.
Dr Dohlad further explained, “Some users may also experience nausea or vomiting, which can expose teeth to stomach acid and weaken enamel over time, further increasing the risk of decay and sensitivity.”
Dentists have observed a rise in patients reporting bad breath and dry mouth symptoms, which can swiftly escalate to cavities or infections. Dr Dohlad emphasised the importance of informing dental care providers about any medications being taken.
“Because oral health is closely linked to overall health, collaboration between patients, dentists, and prescribing doctors is key,” Dr Dohlad noted. He suggested that more frequent check-ups and tailored oral care routines could help manage these side effects.
As GLP-1 medications continue to be prevalent, ensuring patients have the necessary information to mitigate oral health risks remains crucial.
Dr Dohlad highlighted the importance of saliva as a natural defence system in the mouth. When saliva levels drop, it can lead to an environment that favours bacterial growth and acid buildup, increasing the likelihood of dental issues.
Dentists recommend addressing dry mouth by staying hydrated and potentially using saliva substitutes. Regular dental visits can help catch early signs of decay or other oral health issues.

Last updated: 29 June 2026, 11:46 am